A Hong Kong man has developed the world’s first-ever human case of the rat version of the hepatitis E virus (HEV), according to research from one of the territory’s leading universities.
There had previously been no evidence that the disease could jump from rats to humans, the University of Hong Kong said yesterday, adding that the discovery has “major public health significance.”
“This study conclusively proves for the first time in the world that rat HEV can infect humans to cause clinical infection,” the university said.
The rat hepatitis E virus is very distantly related to human hepatitis E virus variants, the university said.
The disease was found in a 56-year-old man who persistently produced abnormal liver function tests following a liver transplant.
He could have contracted the illness through food infected by rat droppings, researchers said, according to details of the findings reported in the South China Morning Post.
The man lived in a housing estate where there were signs of a rat infestation outside his home, the newspaper said.
He is now recovering after being treated for the virus, it said.
The human version of hepatitis E is a liver disease that affects 20 million people globally each year, according to the WHO.
It is usually spread through contaminated drinking water. Symptoms include fever, vomiting and jaundice, and in rare cases, liver failure.
Rodent problems in Hong Kong have escalated in recent months because of a sustained spell of hot and humid weather.
Hong Kong has been hit hard by disease outbreaks in the past. In 2003, almost 300 people died from SARS.
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