Mauresmo said she felt under no extra pressure as defending champion.
"It was good. I felt pretty happy to go on the court and to play first and to be able to, right from the first day, go on court and defend a title," Mauresmo said.
Perry, a 22-year-old US player who finished last year at No. 43 in the rankings, let Mauresmo off the hook with 21 unforced errors.
Seventh-seeded Elena Dementieva of Russia advanced with a 6-1, 6-2 victory over Stephanie Foretz of France. Tenth-seededNicole Vaidisova beat Jill Craybas 6-4, 5-7, 6-1.
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