Lo Duca had a game-winning homer at Milwaukee on Saturday, and has five RBIs on the trip.
Hector Luna and Gary Bennett each had two hits and an RBI for the Cardinals, who lost for just the fifth time in 20 games against the Mets since 2003.
Diamondbacks 5, Padres 2
At Phoenix, Eric Byrnes and Chad Tracy hit back-to-back home runs, and the Diamondbacks moved into first place in the NL West. With their fifth straight win over San Diego this season, the Diamondbacks took a half-game lead over the Padres and the Colorado Rockies.
Arizona won on a night that starting pitcher Orlando Hernandez left with a mid-back strain in the third inning. Jason Grimsley (1-1) pitched three scoreless innings and was credited with the victory. Jose Valverde pitched the ninth for his 12th save in 13 opportunities.
Jake Peavy (3-4) allowed three runs and six hits -- including the homers to Byrnes and Tracy -- in five innings.
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