Sleep loss may be more serious than previously thought, causing a permanent loss of brain cells, research suggests.
In mice, prolonged lack of sleep led to 25 percent of certain brain cells dying, according to a study in The Journal of Neuroscience.
If the same is true in humans, it may be futile to try to catch up on missed sleep, say US scientists.
Photo: Reuters
照片：路透社
They think it may one day be possible to develop a drug to protect the brain from the side-effects of lost sleep.
The study looked at lab mice that were kept awake to replicate the kind of sleep loss common in modern life, through night shifts or long hours in the office.
A team at the University of Pennsylvania School of Medicine studied certain brain cells which are involved in keeping the brain alert.
After several days of sleep patterns similar to those followed by night workers — three days of night shifts with only four to five hours sleep in 24 hours — the mice lost 25 percent of the brain cells.
(Liberty Times)
研究顯示，喪失睡眠會導致大腦細胞永久流失，可能比過去想像的還要嚴重。
針對老鼠的實驗顯示，長期缺乏睡眠導致百分之二十五的特定大腦細胞垂死，根據《神經科學期刊》刊登的研究。
如果相同的情況發生在人類身上，試圖彌補失去的睡眠可能沒有用，美國科學家說。
他們認為，未來或許可能研發出能保護大腦不受喪失睡眠副作用影響的藥物。
這份研究觀察保持醒覺的實驗室老鼠，複製現代生活中因上夜班或長時間工作而常見的喪失睡眠情況。
賓州大學醫學院的團隊，研究與保持大腦警覺相關的大腦細胞。
經過幾天類似夜間工作者的睡眠模式，也就是三天上夜班、每二十四小時只睡四到五小時，老鼠喪失百分之二十五的大腦細胞。
（自由時報／翻譯：自由時報國際新聞中心）
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1. 我不夠快。 ˇ I wasn’t fast enough. χ I wasn’t enough fast. 註：enough用作副詞時，一般放在它修飾的形容詞或其他副詞後面。例如： The tea is hot enough.（茶是夠熱。） He did not work hard enough.（他不夠用功。） 但enough用作形容詞時，前置或後置都可以。例如： There is enough food (/food enough) for us. 2. 今晚七時我們將開董事會。 ˇ We are having a board meeting at seven o’clock this evening. ˇ We are having a board meeting this evening, at seven o’clock. χ We are having a board meeting this evening at seven o’clock. 註：如果有多個時間副詞，一般單位大的放在單位小的後面。例如： I was born in May 1939. The meeting was held at five o’clock yesterday afternoon. 但如果大的單位是說話者強調的重點，則可以放在前面，但後面要有逗號，表示停頓。例如： He arrived yesterday afternoon, at about five o’clock. 3. 我生於麻州波士頓。 ˇ I was born in Boston, Massachusetts. χ I was born in Massachusetts, Boston. 註：一般而言，地點副詞的位置，範圍大的放在範圍小的後面。例如： Before
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