Academia Sinica yesterday approved the resignation of distinguished research fellow Chen Ching-shih (陳慶士) after news of research misconduct in eight of his published papers was made public by the Ohio State University, where he previously served as a cancer researcher.
Academia Sinica said in a statement that it is sorry to hear about the incident, but added that Chen’s misconduct occurred before he became head of Academia Sinica’s Institute of Biological Chemistry in August 2014.
The institution’s Research Ethics Committee would still look into work he performed while serving at the academy, the statement added.
Chen’s resignation from the Academia Sinica comes after academic journal Science and the university issued separate reports on Friday regarding the findings of research misconduct that led to his resignation as a cancer researcher from the university last year.
The reports said the investigation found Chen had “intentionally committed research misconduct” in 14 instances in eight journal articles, and was guilty of “deviating from the accepted practices of image handling and figure generation and intentionally falsifying data.”
Chen admitted to the charges and resigned in September last year, the university said.
The university said it has requested an “immediate retraction” of the papers, published between 2006 and 2014, that contain the fabricated data.
However, the implications of the misconduct go beyond unreliable academic papers, as Chen’s work had raised millions of US dollars in funding and led to multiple patents and the establishment of two compounds in clinical trials.
The university said it immediately shut down a clinical trial of one of Chen’s anti-cancer agents that Arno Therapeutics Inc had been conducting after obtaining exclusive rights to test the agents.
A spokesperson for the company said that issues with Chen’s papers had “zero impact” on its drug development efforts, Science said.
The university said it “hired an external consultant who validated that Chen’s research misconduct did not affect the Arno licensed compounds developed in his lab.”
“Patient safety was never compromised,” the university’s statement said.
The university said it has forwarded the investigation to federal authorities, meaning Chen could continue to be investigated for his actions.
Academia Sinica first became aware of the matter about a year ago, but it had limited access to Chen’s questionable articles because the university did not reveal its investigation on its Web site until Friday, Academia Sinica Central Academic Advisory Committee executive secretary Henry Sun (孫以瀚) said yesterday.
This is the worst punishment a Taiwanese academic has ever received from a foreign institution, dealing a heavy blow to the nation’s image in international academia, Sun said.
Sun quoted Chen as saying that his laboratory staff “beautified” data to make their research look better, and that he was responsible for lax supervision.
Yesterday morning, Chen’s profile was accessible on the Institute of Biological Chemistry’s Web site, but it was later taken down after Chen tendered his verbal resignation to Academia Sinica president James Liao (廖俊智).
Meanwhile, China Medical University, where Chen in February temporarily served as the director of its Institute of New Drug Development, yesterday said it is unclear about the matter and is collecting information about the case.
Before Chen returned to Taiwan to serve as director of the Institute of Biological Chemistry in August 2014 — a position he held until August last year — he had taught at the Ohio State University’s College of Pharmacy, the University of Rhode Island and the University of Kentucky.
Specializing in medicinal chemistry, cancer studies, biological chemistry and translational medicine, Chen has received research awards from the US Prostate Cancer Foundation and the Hearst Foundation, and is a fellow at the American Association for the Advancement of Science.
In April last year, he and National Cheng Kung University researchers found a relation between vitamin E and cancer prevention, and created an anti-tumor agent that is 20 times more efficient than previous ones, which was then considered a potential opportunity to develop a new anti-cancer drug.
A Chinese aircraft carrier group entered Japan’s economic waters over the weekend, before exiting to conduct drills involving fighter jets, the Japanese Ministry of Defense said yesterday. The Liaoning aircraft carrier, two missile destroyers and one fast combat supply ship sailed about 300km southwest of Japan’s easternmost island of Minamitori on Saturday, a ministry statement said. It was the first time a Chinese aircraft carrier had entered that part of Japan’s exclusive economic zone (EEZ), a ministry spokesman said. “We think the Chinese military is trying to improve its operational capability and ability to conduct operations in distant areas,” the spokesman said. China’s growing
BUILDUP: US General Dan Caine said Chinese military maneuvers are not routine exercises, but instead are ‘rehearsals for a forced unification’ with Taiwan China poses an increasingly aggressive threat to the US and deterring Beijing is the Pentagon’s top regional priority amid its rapid military buildup and invasion drills near Taiwan, US Secretary of Defense Pete Hegseth said on Tuesday. “Our pacing threat is communist China,” Hegseth told the US House of Representatives Appropriations Subcommittee on Defense during an oversight hearing with US General Dan Caine, chairman of the Joint Chiefs of Staff. “Beijing is preparing for war in the Indo-Pacific as part of its broader strategy to dominate that region and then the world,” Hegseth said, adding that if it succeeds, it could derail
COMPLIANCE: The SEF has helped more than 3,900 Chinese verify documents, indicating that most of those affected are willing to cooperate, the MAC said More than 3,100 spouses from China have submitted proof of renunciation of their Chinese household registration, the Mainland Affairs Council (MAC) said yesterday. The National Immigration Agency has since April issued notices to spouses to submit proof that they had renounced their Chinese household registration on or before June 30 or their Taiwanese household registration would be revoked. People having difficulties obtaining such a document can request an extension of the deadline or submit a written affidavit in lieu of it. The council said it would hold a briefing at 2:30pm on Friday at the immigration agency’s Taichung office in cooperation with the
The government-funded human papillomavirus (HPV) vaccination is to be expanded to boys at junior-high school starting in September, the Health Promotion Administration (HPA) said yesterday. The Taiwan Society of Otorhinolaryngology, Head and Neck Surgery, the Taiwan Association of Obstetrics and Gynecology, the Taiwan Immunization Vision and Strategy, the Infectious Diseases Society of Taiwan, the Taiwan Head and Neck Society, the Formosa Cancer Foundation and the National Alliance of Presidents of Parents Associations held a joint news conference in Taipei yesterday to raise public awareness about the risks of HPV infection, regardless of gender. Invited to give an address, HPA Director-General Wu Chao-chun