Fri, Nov 17, 2006 - Page 3 News List

Taiwan Quick Take: Limitations found for Prozac

STAFF WRITER WITH AGENCIES

Prozac, a common medication used to combat depression, has been found to be less effective on patients with a specific gene set. People who have taken Prozac for two months but have shown no sign of improvement should opt for another treatment, says a medical report released by the Taipei Veterans General Hospital (TVGH). Tsai Shih-jen (蔡世仁), section chief of General Psychiatry at TVGH, said those with major depression carry genes that mitigate serotonin reuptake transporters, enhance monoamine oxidase, disrupt brain-derived neurotrophic factors, or generate serotonin 1A receptors that are more likely to be "Prozac-resistant."

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