Brenes scored again in the second minute of the second half, Alvaro Saborio boosted Costa Rica’s lead on a penalty kick in the 51st minute after Guyana’s Walter Moore was ejected and Cristian Bolanos made it 5-0 in the 60th minute.
Celso Borges scored for the Ticos in the 69th minute and Saborio netted the last marker in the 76th.
Mexico’s Oribe Peralta opened the scoring in the 64th minute against the Salvadorans and Javier Hernandez added an insurance goal in the 84th minute to complete a perfect qualifying run for the Tricolores.