A forum of scientific advisers set up by the Indian government has told authorities about minor mutations in some samples of SARS-CoV-2, the virus that causes COVID-19, that could “possibly evade immune response” and require more study, a leader of the forum said.
However, the advisers said that while they were flagging the mutations, there was no reason to believe that they were expanding or could be dangerous.
Scientists are studying what led a surge in cases in India in the past few weeks and particularly whether a variant first detected in the country, called B.1.617, is to blame.
Photo: AP
The WHO has not declared the Indian variant a “variant of concern,” as it has done for variants first detected in the UK, Brazil and South Africa.
However, on Tuesday last week, the organization said that its early modeling, based on genome sequencing, suggested that B.1.617 had a higher growth rate than other variants circulating in India.
The forum of advisers, known as the Indian SARS-CoV-2 Genetics Consortium (INSACOG), has now found more mutations in the virus that it thinks need to be tracked closely.
“We are seeing some mutation coming up in some samples that could possibly evade immune responses,” said Shahid Jameel, a virologist and chairman of INSACOG’s scientific advisory group.
Jameel did not say if the mutations have been seen in the Indian variant or any other strain.
“Unless you culture those viruses and test them in the lab, you can’t say for sure. At this point, there is no reason to believe that they are expanding or if they can be dangerous, but we flagged it so that we keep our eye on the ball,” he said.
INSACOG brings together 10 national research laboratories.
India reported more than 400,000 new COVID-19 cases for the first time on Saturday. The rampaging infections have collapsed its health system in places including the capital of New Delhi, with shortages of medical oxygen and hospital beds.
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