Under the ITC complaint, Creative asked the agency to block imports of iPods, which are manufactured abroad.
The ITC will reach a conclusion as soon as possible, setting a target date within 45 days of the investigation's launch, Creative said.
The probe is the latest development in an increasingly twisted patent battle between the two companies.
In court documents, Apple has maintained no wrongdoing and has since filed two patent-infringement countersuits against Creative.
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