The new H1N1 influenza virus bears a disturbing resemblance to the virus strain that caused the 1918 flu pandemic, with a greater ability to infect the lungs than common seasonal flu viruses, researchers reported on Monday.
Tests in several animals confirmed other studies that have shown the new swine flu strain can spread beyond the upper respiratory tract to go deep into the lungs — making it more likely to cause pneumonia, the international team said.
In addition, they found that people who survived the 1918 pandemic seem to have better defenses against the virus, again confirming the work of other researchers.
“When we conducted the experiments in ferrets and monkeys, the seasonal virus did not replicate in the lungs,” said Yoshihiro Kawaoka of the University of Wisconsin, who led the study.
The H1N1 virus replicates significantly better in the lungs.”
The new swine flu virus has caused the first pandemic of the 21st century, infecting more than 1 million people, according to estimates, and killing at least 500. The WHO says it is causing mostly moderate disease, but Kawaoka said that does not mean it is like seasonal flu.
“There is a misunderstanding about this virus,” he said in a statement. “There is clear evidence the virus is different than seasonal influenza.”
Writing in the journal Nature, Kawaoka and colleagues noted that the ability to infect the lungs is a characteristic of other pandemic viruses, especially the 1918 virus, which is estimated to have killed between 40 million and 100 million people.
They tested the virus in blood samples taken from nursing home residents and workers in 1999 in California, Wisconsin, the Netherlands and Japan.
People born before 1920 had a strong antibody response to the new H1N1 virus, meaning their body “remembered” it from infection early in life. This finding supports a study published in Nature last August that found that people who survived the 1918 pandemic still had immune protection against that virus.
Flu viruses change constantly, which is why people can be re-infected and why the vaccine must be changed regularly. Current seasonal strains of H1N1 are distant cousins of both the 1918 pandemic strain and the new H1N1 strain.
“Our findings are a reminder that swine-origin influenza viruses have not yet garnered a place in history, but may still do so, as the pandemic caused by these viruses has the potential to produce a significant impact on human health and the global economy,” the researchers wrote.
Republican US lawmakers on Friday criticized US President Joe Biden’s administration after sanctioned Chinese telecoms equipment giant Huawei unveiled a laptop this week powered by an Intel artificial intelligence (AI) chip. The US placed Huawei on a trade restriction list in 2019 for contravening Iran sanctions, part of a broader effort to hobble Beijing’s technological advances. Placement on the list means the company’s suppliers have to seek a special, difficult-to-obtain license before shipping to it. One such license, issued by then-US president Donald Trump’s administration, has allowed Intel to ship central processors to Huawei for use in laptops since 2020. China hardliners
Conjoined twins Lori and George Schappell, who pursued separate careers, interests and relationships during lives that defied medical expectations, died this month in Pennsylvania, funeral home officials said. They were 62. The twins, listed by Guinness World Records as the oldest living conjoined twins, died on April 7 at the Hospital of the University of Pennsylvania, obituaries posted by Leibensperger Funeral Homes of Hamburg said. The cause of death was not detailed. “When we were born, the doctors didn’t think we’d make 30, but we proved them wrong,” Lori said in an interview when they turned 50, the Philadelphia Inquirer reported. The
RAMPAGE: A Palestinian man was left dead after dozens of Israeli settlers searching for a missing 14-year-old boy stormed a village in the Israeli-occupied West Bank US President Joe Biden on Friday said he expected Iran to attack Israel “sooner, rather than later” and warned Tehran not to proceed. Asked by reporters about his message to Iran, Biden simply said: “Don’t,” underscoring Washington’s commitment to defend Israel. “We are devoted to the defense of Israel. We will support Israel. We will help defend Israel and Iran will not succeed,” he said. Biden said he would not divulge secure information, but said his expectation was that an attack could come “sooner, rather than later.” Israel braced on Friday for an attack by Iran or its proxies as warnings grew of
A prominent Christian leader has allegedly been stabbed at the altar during a Mass yesterday in southwest Sydney. Bishop Mar Mari Emmanuel was saying Mass at Christ The Good Shepherd Church in Wakeley just after 7pm when a man approached him at the altar and allegedly stabbed toward his head multiple times. A live stream of the Mass shows the congregation swarm forward toward Emmanuel before it was cut off. The church leader gained prominence during the COVID-19 pandemic, amassing a large online following, Officers attached to Fairfield City police area command attended a location on Welcome Street, Wakeley following reports a number