The Eagles (6-5) inched ahead of the Dallas Cowboys (5-5), who had a bye, with rookie quarterback Nick Foles throwing for 298 yards and running for a touchdown.
Washington, last season’s division champions, fell to 3-7.
“Nobody on the team will give up, I can guarantee you that, but this one if is a tough one to swallow,” Washington Redskins wide receiver Santana Moss said.
Oakland’s undrafted rookie quarterback Matt McGloin threw three touchdown passes in his first career start as the Raiders (4-6) beat the struggling Houston Texans (2-8) 28-23.
The Buffalo Bills (4-7) snapped a three-game skid with a 37-14 thrashing of American Football Conference East rivals the New York Jets (5-5), while the Tampa Bay Buccaneers (2-8) recorded their second straight win with a 41-28 rout of the Atlanta Falcons (2-8).
The Arizona Cardinals (6-4) stayed in the playoff hunt with a 27-14 victory over the Jacksonville Jaguars (1-9), the Miami Dolphins (5-5) defeated the San Diego Chargers (4-6) 20-16 and the Denver Broncos (9-1) downed the previously unbeaten Kansas City Chiefs (9-1) 27-17.