Fri, Oct 18, 2013 - Page 20 News List

Ex-football players show profound brain problems

Reuters, London

Scientists have found “profound abnormalities” in scans of brain activity in a group of retired football players, adding to evidence indicating that repeated blows to the head can trigger longer-term aggression and dementia.

Although the former NFL players in the study were not diagnosed with any neurological conditions, brain-imaging tests showed unusual activity that correlated with the number of times they had left the field with a head injury.

Adam Hampshire at Imperial College London, who led the study, said the ex-NFL players showed “some of the most pronounced abnormalities in brain activity” he had ever seen.

A growing body of scientific research shows that repeated knocks to the head can lead to a condition known as chronic traumatic encephalopathy, which can lead to loss of decision-making control, aggression and dementia.

These latest findings, published in the Nature journal Scientific Reports, suggest players also face a risk of subtle neurological deficits that would not necessarily show up on normal clinical tests.

John Hardy at University College London’s Institute of Neurology said the findings showed what he and others have long suspected — that common dysfunctional behavior among former sportsmen such as footballers and boxers is related to sub-clinical brain injuries.

Hampshire’s study involved 13 former NFL professionals who felt they were suffering brain problems affecting everyday life.

While their brain activity was measured using functional magnetic resonance imaging, the former players and 60 healthy volunteers were given a test that involved rearranging colored balls in tubes.

The NFL group performed worse on the test than the healthy volunteers, but the difference was modest, according to Hampshire and colleagues at the University of Western Ontario, Canada, who collaborated on the study.

However, the scans showed unusual patterns of brain activity in the frontal lobe.

Hampshire said that levels of brain abnormality seen in the ex-players correlated strongly with the number of head impacts they had suffered that were severe enough to warrant them being taken out of play.

“This means that it is highly likely that damage caused by blows to the head accumulate towards an executive impairment in later life,” he said.

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