Villar connected off Joe Saunders (11-14) for his first career homer. The Astros scored six times in the first three innings to chase Saunders. The left-hander has lost six of his past eight decisions.
Chris Carter and Jose Altuve each had three of the Astros’ 17 hits. Houston’s 10 extra-base hits were a season high, eclipsing the previous mark of nine — also set against the Mariners.
Altuve and rookie L.J. Hoes both had three RBIs. Jordan Lyles (7-7) held Seattle in check through six innings.
In interleague play, it was:
‧ Pirates 5, Rangers 4