Baltimore pitcher Jim Johnson walked Maicer Izturis with the bases loaded in the 11th inning to force in the tiebreaking run, giving Toronto a 6-5 win and ending the Orioles remarkable streak of 17 straight wins in extra innings.
Detroit’s Jose Valverde returned to the Tigers team with a save, securing a 7-5 win over Kansas City.
Valverde was not offered a contract after a nightmare postseason last year, but has worked his way back up from the minors.
Cincinnati pitcher Mat Latos retired 15 of the first 16 batters he faced, leading the Reds to a 1-0 win over the Chicago Cubs.
New York’s Jordany Valdespin hit a grand slam in the 10th inning as the Mets rallied past the Los Angeles Dodgers 7-3.
San Diego’s Edinson Volquez pitched seven strong innings, helping the Padres to a 2-1 win over Milwaukee, ending the Brewers’ nine-game winning streak.
Chicago’s Alex Rios hit a two-run homer as the White Sox beat Cleveland 3-2 to stop a four-game losing streak.
Houston’s Chris Carter, Ronny Cedeno and Brandon Laird homered as the Astros beat Seattle 10-3.