Napoli briefly lost touch with the top after a 2-0 defeat at Juventus last week, but Hamsik’s strike was enough to secure the points.
In Sunday’s other late match, AS Roma were stunned 3-2 by Udinese.
The Giallorossi had built a 2-0 lead thanks to a brace from Erik Lamela in the space of two first-half minutes, but Zdenek Zeman’s side were pegged back by Maurizio Domizzi’s 32nd-minute goal and then stunned by a brace, including an 88th-minute penalty, by Antonio di Natale.
Also on Sunday, Parma won 3-1 at Torino, Cagliari won 1-0 away at UC Sampdoria, while Delfino Pescara 1936 were held to a goalless draw by Atalanta BC.
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