The Athletics seized the lead in the first inning when leadoff hitter Coco Crisp singled to right field, advanced on a walk and scored from second base on a single by Yoenis Cespedes.
Crisp leaped high over the centerfield wall to made a grab off a Prince Fielder deep fly ball to deny the Detroit slugger a homer in the second inning.
“Coco robbing the homer kind of set the tone,” Anderson said.
Smith connected on his homer in the fifth inning to boost Oakland’s lead to 2-0 and three Athletics relief pitchers combined to strike out five while allowing only two hits in three scoreless innings after Anderson was lifted.
Australian right-handed relief pitcher Grant Balfour entered in the ninth inning, facing the heart of the Tigers’ batting order.
Balfour struck out Omar Infante and, after surrendering a single to Miguel Cabrera, induced Prince Fielder to hit into a game-ending double play.