Dodgers 2, Diamondbacks 1
At Los Angeles, pinch-hitter Olmedo Saenz singled home the winning run with two outs in the ninth inning and Los Angeles snapped Arizona's six-game winning streak.
Rafael Furcal led off the ninth with a single against Brandon Lyon (2-1), then advanced to third on Juan Pierre's sacrifice and Wilson Valdez's groundout. Jeff Kent was intentionally walked in front of Saenz, who drove a 1-1 pitch up the middle while batting for winning pitcher Takashi Saito (1-0).
Rockies 9, Giants 7
At San Francisco, Matt Holliday homered and hit a three-run double after being moved from fifth to third in the lineup, and Colorado beat San Francisco.
Alberto Arias (1-0) threw 3 2-3 scoreless innings of relief to win his major league debut, and Brian Fuentes earned his fifth save.
Phil Hughes was working on a no-hitter in the seventh inning of his second major league start when a hamstring injury cost him a chance to make history.
The Yankees' prized prospect is expected to miss four to six weeks, a sour end to an otherwise encouraging night for the last-place club. New York responded to criticism from owner George Steinbrenner in a big way on Tuesday with a 10-1 rout of the Texas Rangers.
Indians 12, Blue Jays 4
At Cleveland, rocked for three homers in the first inning, C.C. Sabathia buckled down to stay unbeaten and Jhonny Peralta had a career-high five RBIs for the hosts.
After enduring a season-opening month of snow, postponements and travel, Cleveland began May with a comeback victory, scoring nine consecutive runs to win for the eighth time in nine games.
Athletics 5, Red Sox 4
At Boston, Dan Johnson doubled home the winning run in the 10th inning after Jonathan Papelbon had his first blown save opportunity of the season and Oakland stopped surging Boston.
The Red Sox had won four of five games and began the day with the best record in baseball but wasted a 4-2 lead and another strong performance by Curt Schilling.
Tigers 5, Orioles 4
At Detroit, pinch-hitter Sean Casey hit a tiebreaking single with one out in the eighth inning to lift the Detroit.
Craig Monroe also homered for Detroit and Placido Polanco 4-for-5 with two RBIs. The Tigers rallied for two runs in the eighth against Danys Baez (0-1).
Twins 9, Devil Rays 1
At St. Petersburg, Florida, Sidney Ponson pitched seven impressive innings and Michael Cuddyer drove in two runs for Minnesota before leaving with an injury.
Ponson (2-3) gave up five hits. Both of his wins this season have come against the Devil Rays.
Angels 7, Royals 5
At Kansas City, Missouri, Vladimir Guerrero hit a first-inning grand slam and surging Los Angeles held on to beat reeling Kansas for the Angeles' 10th victory in 12 games.
The first three Angels hitters singled on Zack Greinke's first seven pitches to load the bases. Greinke quickly went to 3-0 on Guerrero. Then after a called strike, the seven-time All-Star hit the next pitch sailing 130m over the fence in left-center for his fifth grand slam.
Mariners 5, White Sox 2
At Seattle, Richie Sexson hit a two-run home run and Jarrod Washburn allowed two singles and two solo home runs in seven innings to lead Seattle past Chicago for its sixth victory in seven games.
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