Melvin Mora had two hits, scored a run and drove in one for the Orioles.
Brian Roberts, who came in batting .136 (3-for-22), went 2-for-4 and scored twice.
Cabrera (1-1) gave up seven hits, struck out five and walked none. Making his first start in the majors since 2004, Chad Durbin (0-1) yielded six runs and nine hits in four-and-two-thirds innings.
Yankees 8, Twins 2
At Minneapolis, Alex Rodriguez homered for the third straight game for New York, and Carl Pavano worked seven efficient innings to get his first win since May 2005.
Bobby Abreu went 3-for-5 with a two-run homer and four RBIs for New York. Johnny Damon had two hits in his first start in a week due to a calf strain.
Blue Jays 9, Royals 1
At Toronto, A.J. Burnett and three relievers combined on a four-hitter and Vernon Wells homered to help Toronto win its home opener.
Lyle Overbay hit a three-run double for the AL East-leading Blue Jays, who have averaged seven runs a game in the first six games. Toronto has won three straight.
John Buck homered off Burnett for Kansas City, which played the first of a 10-game road trip.
Burnett (1-1) allowed just three hits, struck out five and walked three in six-and-two-thirds innings.
Rangers 8, Devil Rays 4
At Arlington, Texas, Ian Kinsler went 4-for-4 and drove home the tiebreaking run in the big inning for Texas.
Kinsler's RBI single in the sixth put the Rangers ahead 3-2 and started a six-run outburst with two outs.
He was the first of six straight batters that reached against two Tampa Bay relievers who didn't record an out.
White Sox 4, Athletics 1
At Oakland, California, Scott Podsednik broke a tie with his fifth-inning solo homer and Jim Thome also homered to help Chicago spoil Oakland's home opener.
RSS