Adrian Peterson broke his collarbone on a fourth-quarter dive into the end zone on Saturday during the 23rd-ranked Oklahoma Sooners' 34-9 victory over Iowa State.
The injury occurred at the end of a 53-yard touchdown run with about 6:40 left in the game. The junior ran for 183 yards and two touchdowns playing for the first time in years before his father, who had spent about eight years in federal prison for money laundering.
"Just diving into the end zone and when he landed, he landed wrong," Oklahoma coach Bob Stoops said. "At this point it looks like the best thing, the earliest he would be ready to play, would be a bowl game."
Peterson started strong with a 40-yard gain on his first carry to set up his 6-yard TD run two plays later.
His father, Nelson Peterson, watched it all from the stands just nine days after he was released from an Oklahoma City halfway house. He never saw his son play in high school or as he racked up an NCAA freshman record 1,925 rushing yards and finished second in the 2004 Heisman voting.
Paul Thompson threw for 195 yards and two touchdowns to Malcolm Kelly as Oklahoma (4-2, 1-1 Big 12) bounced back from a 28-10 loss to Texas. Iowa State fell to 3-4, 0-3.
No. 11 Auburn 27, No. 2 Florida 17
At Auburn, Alabama, the Auburn Tigers scored on a blocked punt, a last-play fumble return and a safety to beat the Gators leave the Southeastern Conference without an unbeaten team.
The Tigers (6-1, 4-1) failed to score an offensive touchdown. Instead, they turned in a dominant defensive performance in the second half and benefited from Chris Leak's fumble deep in Auburn territory that killed a chance for at least a go-ahead field goal.
Florida coach Urban Meyer challenged the call arguing that it was an incomplete pass but replay officials let the play stand.
Eric Brock's late interception of Leak's pass set up the last of John Vaughn's four field goals, a 39-yarder with 31 seconds left.
No. 3 USC 28, Arizona State 21
At Los Angeles, Chauncey Washington did nearly all the work on a 74-yard, fourth-quarter touchdown drive that lifted the Trojans to a victory.
The junior tailback scored on a 2-yard run with 4:29 remaining to cap the 14-play drive that ate up nearly seven minutes. He gained 64 yards on 10 carries as the Trojans (6-0, 4-0 Pac-10) went strictly with a power running game following an ineffective performance by quarterback John David Booty.
Washington made his first career start a big one, finishing with a career-high 108 yards on 22 carries.
Booty completed 12 of 25 passes for 148 yards and two touchdowns. He threw only one interception, but Keno Walter-White returned it 37 yards for a touchdown for the Sun Devils (3-3, 0-3) with 3:18 left in the third quarter to tie the game 21 before Washington's last touchdown.
No. 1 Ohio St. 38, Michigan St. 7
At East Lansing, Michigan, Troy Smith did nothing to hurt his Heisman candidacy and the Ohio State defense was dominant against Michigan State.
The top-ranked Buckeyes (7-0, 3-0 Big Ten) extended the nation's longest winning streak to 14 games and had little trouble with the fading Spartans (3-4, 0-3).
Michigan State entered the game averaging 31 points per contest. But the Spartans gained just 79 yards in the first half and trailed 24-0 at the break.
Smith completed 15 of 22 passes for 234 yards and two touchdowns to boost his Heisman Trophy resume. Anthony Gonzalez caught seven passes for 118 yards and a TD, and Ted Ginn Jr. returned a punt 60 yards for a touchdown.