Fullback Bevan Fortuin, flanker Hilton Lobberts, center Jaco Pretorius and utility back Francois Steyn are the four new players.
White left out prop Os du Rand, lock Victor Matfield, scrumhalf Fourie du Preez, winger Bryan Habana, fullback Percy Montgomery and winger Breyton Paulse. They were all rested after a tough Tri-Nations test series against New Zealand and Australia.
Fortuin is one of the star players for the Currie Cup finalist Cheetahs, while Lobberts has played with the South African under-21 team.
Center Wynand Olivier withdrew from the Bulls team just before the Currie Cup final with a recurrence of a knee injury. He may miss the tour.
"We have got to plan for the World Cup," White said. "It is an opportunity for blooding new caps, as well as giving some youngsters a chance to put up their hands for France next year."
Springbok squad: Johan Ackermann, B.J. Botha, Gary Botha, Jacques Cronje, Deon Carstens, Jean de Villiers, Jaque Fourie, Bevan Fortuin, Butch James, Ricky Januarie, Hilton Lobberts, Johann Muller, Akona Ndungane, Wynand Olivier, Ruan Pienaar, J.P. Pietersen, Jaco Pretorius, Andre Pretorius, Chiliboy Ralepelle, Danie Rossouw, Lawrence Sephaka, John Smit (captain), Juan Smith, Pierre Spies, Francois Steyn, Albert van den Berg, C.J. van der Linde, Pedrie Wannenburg.



