Miguel Cabrera hit one of four Florida homers and the rookie-laden Marlins roughed up Andy Pettitte for 10 runs and 13 hits on Tuesday in an 11-2 rout of the Houston Astros.
Josh Willingham connected twice, Mike Jacobs added a three-run shot and Hanley Ramirez had four hits and three RBIs. Florida, with six rookies in its starting lineup and a major league-low payroll of about $15 million, gave first-year manager Joe Girardi his first win.
Things went bad early for Pettitte, who allowed seven earned runs in 4 2-3 innings.
Cabrera, who was 0-for-4 in Monday's 1-0 loss, hit a two-run homer to right in the first. He also doubled and scored in the fifth.
Willingham, who spent most of last season at Triple-A Albuquerque, got his second major league home run when his long fly bounced off the left-field wall two pitches later. Willingham also connected against Chad Qualls in the sixth.
Pettitte, who ended last season with a seven-game winning streak, hadn't allowed three homers in a game since 2003 with the New York Yankees.
Brewers 7, Pirates 5
At Milwaukee, Gabe Gross homered as a pinch-hitter in his first at-bat with Milwaukee and Chris Capuano pitched six solid innings.
With runners at second and third in the ninth inning, Pirates pinch-hitter Freddy Sanchez hit a liner up the middle that appeared headed for center field and a tying, two-run single.
But closer Derrick Turnbow reacted quickly and caught it, then retired Nate McLouth on a popup to end the game.
Gross' two-run shot in the sixth landed on a catwalk in right-center, putting the Brewers ahead 5-2. J.J. Hardy added an RBI single later in the inning.
Capuano, an 18-game winner last year, gave up two runs and struck out seven for the win and Turnbow worked the ninth for his second save in two days.
Gross became the fifth player in Brewers history to hit a home run in his first plate appearance for the team.
Dodgers 5, Braves 4
At Los Angeles, Brad Penny pitched five strong innings, J.D. Drew hit a two-run homer and Los Angeles beat Atlanta on a rainy night for Grady Little's first victory as the Dodgers' manager.
Penny allowed five hits and one run while walking none and striking out eight before giving way to Jae Seo, who worked three innings.
Penny, who threw 92 pitches, didn't allow a hit after the second, retiring 10 of his last 11 batters to earn the win.
Danys Baez pitched the ninth for his first save in place of suspended closer Eric Gagne.
Drew put Los Angeles ahead for good by connecting against loser John Smoltz in the first. The Dodgers got two more runs in the inning on RBI singles by Bill Mueller and Jason Repko.
Brian McCann and Adam LaRoche homered for the Braves.
The Dodgers placed first baseman Nomar Garciaparra on the 15-day disabled list because of a strained muscle in his right side.
Aaron Boone took some glimmer off Chicago's ring ceremony on Tuesday, lifting the Cleveland Indians to an 8-2 victory over the White Sox.
Boone homered, drove in four runs and crashed into catcher A.J. Pierzynski to score a run for Cleveland, which put a damper on another day of celebrations by the World Series champions.
Winner Jake Westbrook allowed two runs and six hits in 6 1-3 innings for the Indians, who put ace lefty C.C. Sabathia on the 15-day disabled list before the game with a strained abdominal muscle.
Victor Martinez also homered for Cleveland as the Indians roughed up loser Freddy Garcia for seven runs and nine hits in four innings. The Indians bounced back from Sunday night's soggy season opener, when they lost 10-4 in a game interrupted nearly three hours by rain.
Blue Jays 6, Twins 3
At Toronto, Roy Halladay outpitched Johan Santana in a matchup of recent Cy Young pitching award winners to lead the new-look Toronto over Minnesota.
The Blue Jays signed Gold Glove catcher Bengie Molina, starter A.J. Burnett and closer B.J. Ryan during an expensive offseason overhaul. They also traded for slugger Troy Glaus and first baseman Lyle Overbay.
The new additions paid off right away. Molina homered off Santana to give Toronto a 3-1 lead. Ryan, signed to a US$47 million, five-year contract, struck out two in a perfect ninth to close it out.
Halladay allowed three runs -- two earned -- and five hits, striking out four and walking none in 7 2-3 innings.
Tony Batista and Shannon Stewart homered for the Twins, who wore "34" patches on their right sleeves to honor Hall of Famer Kirby Puckett, who died March 6 following a stroke.
Rangers 10, Red Sox 4
At Arlington, Texas, Phil Nevin had a three-run homer in the first inning and later chased struggling Red Sox pitcher Tim Wakefield with a two-run single as Texas trounced Boston.
Winner Vicente Padilla allowed only one run and four hits over six innings in his AL debut. Acquired from Philadelphia in an offseason trade, he struck out five and walked two.
Nevin's homer put the Rangers ahead 4-0 in the first, when the first four batters reached base. Mark Teixeira had an RBI single, and Nevin followed with a drive to left field. His two-run single with two outs in the fourth made it 6-0 and finished off Wakefield, who took the loss. Hank Blalock greeted Lenny DiNardo with an RBI single.
Athletics 4, Yankees 3
At Oakland, California, Marco Scutaro singled over left-fielder Hideki Matsui's head in the bottom of the ninth inning to lift Oakland over New York.
Nick Swisher and Eric Chavez homered off Yankees starter Mike Mussina, who struck out six in seven solid innings but failed to earn a decision.
Milton Bradley drew a leadoff walk in the ninth against loser Scott Proctor, then moved to second on Jason Kendall's sacrifice. Swisher was intentionally walked to bring up Scutaro, playing in place of injured shortstop Bobby Crosby. It was Scutaro's sixth game-ending hit during three seasons with the A's.
Reigning AL Rookie of the Year Huston Street pitched a scoreless ninth inning to get the win.
Mariners 10, Angels 8
At Seattle, Richie Sexson had three hits and five RBIs and catcher Kenji Johjima homered in his second straight game as Seattle edged the Los Angeles Angels.
Johjima, the first Japanese catcher in the major leagues, led off Seattle's five-run second inning with a home run. He also had an RBI single in the eighth.
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