No. 1 USC 45, No. 24 Oregon 13
At Eugene, Oregon, Matt Leinart threw for 315 yards and three touchdowns and USC trailed early but took over in the second half for its 25th straight victory.
The Ducks (3-1, 0-1 Pac-10) jumped out to an early 13-0 lead and clung to a 13-10 halftime advantage, but the Trojans (3-0, 1-0) scored 35 unanswered points in the second half.
S Florida 45, No. 9 Louisville 14
At Tampa, Florida, receiver Amarri Jackson ran for two touchdowns and threw for a third to lead South Florida to the biggest victory in the school's brief football history, routing Louisville in the Bulls' Big East debut.
After barely playing a role in the offense in his team's first three games, Jackson was Mr. Versatile in helping South Florida (3-1) beat a ranked opponent for the first time in six tries and stop the nation's third-longest Division I-A winning streak at nine games.
No. 4 Virginia Tech 51,
No. 15 Georgia Tech 7
At Blacksburg, Virginia, Jeff King caught a touchdown pass from Marcus Vick and blocked a field goal that turned into a 78-yard scoring run by D.J. Parker and Virginia Tech routed Georgia Tech.
The Hokies (4-0, 3-0 Atlantic Coast Conference) shut down the vaunted passing game of the Yellow Jackets (3-1, 1-1), turned Georgia Tech's only sustained offensive drive into a special teams touchdown and scored 17 points in a span of 44 seconds.
Parker scooped up a field goal blocked by King and ran 78 yards for a touchdown, giving the Hokies a 14-0 first-quarter lead. And Xavier Adibi and Chris Ellis returned third-quarter interceptions for TDs just 26 seconds apart.
No. 5 Florida 49, Kentucky 28
At Lexington, Kentucky, Chris Leak threw four touchdown passes, all in the first half, and DeShawn Wynn scored four touchdowns as Florida got its offense rolling.
After a blocked punt led to an early Kentucky touchdown, Florida (4-0, 2-0 Southeastern Conference) scored on seven straight possessions and led 49-7 at halftime. Leak, who made his first collegiate start two years ago at Kentucky, was 25-of-32 for 319 yards.
No. 18 Arizona St. 42,
Oregon St. 24
At Corvallis, Oregon, Sam Keller threw for 365 yards and four touchdowns and Derek Hagan had 193 yards receiving for Arizona State in the Pac-10 opener for both teams.
The Sun Devils (3-1) had 475 yards of total offense and scored four touchdowns in the third quarter to pull away. The Beavers (2-2) piled up 525 yards of total offense, but turned the ball over six times.
No. 19 Texas Tech 63, Indiana St. 7
At Lubbock, Texas, Taurean Henderson ran for 141 yards and three touchdowns, and Texas Tech rolled to another early season runaway, beating Division I-AA Indiana State (0-4).
Henderson, the NCAA's active leader in touchdowns, scored on carries of 3, 44 and 6 yards to give Texas Tech (3-0) a 21-0 lead.
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