Jim Edmonds hit his 28th homer for St. Louis.
Chicago's Glendon Rusch (7-8) allowed three runs on seven hits in 6 2-3 innings.
Ryan Dempster pitched the ninth for his 28th save.
Matt Morris (14-9) lost his fourth straight start and fell to 0-4 against the Cubs, allowing four runs on seven hits in six innings.
Giants 5, Dodgers 4
At San Francisco, Barry Bonds hit his first homer after a season-long layoff and Todd Linden singled in the winning run with one out in the bottom of the ninth for San Francisco.
Bonds, who missed most of the year recovering from three operations on his right knee since Jan. 31, hit his 704th career homer in the first off Brad Penny.
Pinch-hitter Ricky Ledee tied the game with a two-run single in the eighth for the Dodgers, but Linden, who had replaced Bonds in left field, got the game-winning hit off Duaner Sanchez (4-6).
Bonds is third on the career homer list, trailing only Babe Ruth (714) and Hank Aaron (755). His homer gave the Giants a 2- lead and came three batters after Randy Winn led off with his career-high 15th home run.
Bonds' first RBI of the season moved him into a ninth-place tie on the career list with Carl Yastrzemski with 1,844.
RSS