Manny Ramirez was hit by a pitch with the bases loaded in the bottom of the 10th inning to give Boston a 3-2 victory over Oakland on Friday night.
Mike Timlin (7-2) got out of a jam in the top of the inning when he retired Mark Ellis on a groundout with Marco Scutaro on third.
Juan Cruz (0-3) allowed a leadoff double to Tony Graffanino in the bottom of the inning. Alejandro Machado pinch ran and took third on Johnny Damon's groundout. Oakland manager Ken Macha then removed left fielder Jay Payton for a fifth infielder, Keith Ginter, who played behind Cruz. Cruz hit Edgar Renteria on the right elbow, then intentionally walked David Ortiz to load the bases.
Keiichi Yabu relieved and hit Ramirez on the left elbow with a 1-1 pitch.
Ortiz tied the score in the sixth with his 43rd homer as Boston maintained an 1.5-game lead in the American League East over New York.
Oakland dropped into second place in the AL West, a game behind Los Angeles, which beat Detroit 7-6 in 12 innings.
Yankees 11, Blue Jays 10
At Toronto, Robinson Cano homered twice and drove in five runs and Alex Rodriguez hit his AL-leading 43rd home run as New York held on to win its fifth straight.
Randy Johnson had his shortest start in more than a decade, ejected in the second inning after complaining to the home plate umpire. The Yankees then took an 11-3 lead.
Johnson allowed three runs and two hits in his shortest regular-season start since July 23, 1993, for Seattle at Cleveland, when he lasted 1 1-3 innings, according to the Elias Sports Bureau. Johnson gave up eight runs in that game.
Cano hit a three-run homer off Dave Bush (5-9) in the third that put New York ahead 5-3 and a two-run shot off Brandon League in the fourth that boosted the lead to 11-3, the first multihomer game of his career.
Scott Proctor (1-0) won for the first time since Oct. 3 last year, also at Toronto, despite allowing four runs and five hits in 3 2-3 innings. Mariano Rivera pitched the ninth for his 40th save.
Vernon Wells hit a three-run homer for Toronto, which has lost four of five.
Indians 3, Royals 1
At Cleveland, Casey Blake and Grady Sizemore hit back-to-back homers in the fifth inning and Cleveland beat Kansas City to maintain its AL wild-card lead.
Scott Elarton (10-7) gave up one run and five hits in 7 2-3 innings as Cleveland won for the 10th time in 11 games. The Indians remained a half-game ahead of New York in the wild-card race and 4.5 games behind first-place Chicago in the AL Central.
Bob Wickman worked the ninth for his 42nd save, completing a six-hitter.
Mark Teahen homered for the Royals, who lost their 97th game, seven shy of the team record set last season.
Aaron Boone drew a leadoff walk in the fifth against Jimmy Gobble (1-1) and Blake homered for a 2-1 lead. Sizemore followed with his 20th homer.
White Sox 2, Twins 1, 10 innings
At Minneapolis, Joe Crede drove in the go-ahead run with an infield single in the 10th for Chicago, which won for the second time in eight games and maintained their 4{-game lead over Cleveland.
Bobby Jenks (1-0) pitched the final 1 1-3 innings for his first major league win.
Jermaine Dye and A.J. Pierzynski started the 10th with singles, and Jesse Crain (10-5) made an error when he couldn't handle Juan Uribe's sacrifice bunt, loading the bases. Crede followed with a liner that hit Crain's leg and bounced away, scoring Dye.
Chicago's Jon Garland pitched eight strong innings, allowing six hits and one run. He struck out six and walked one. The right-hander hasn't won on the road since July 17 and is 1-4 in his last seven starts.
Jacque Jones homered for the Twins.
Angels 7, Tigers 6, 12 innings
At Anaheim, California, pinch-hitter Robb Quinlan singled past a drawn-in infield in the bottom of the 12th with the bases loaded, giving Los Angeles the win and sole possession of first place in the AL West.
Chris Shelton, Placido Polanco and Carlos Pena accounted for all of Detroit's runs with homers against John Lackey, who had allowed only two home runs in his previous 17 starts.
Vladimir Guerrero led off the 12th with a single and took second when Vic Darensbourg (1-1) fielded Darin Erstad's sacrifice bunt and pulled Shelton off first base with his throw. The runners advanced on Bengie Molina's bunt, and Maicer Izturis was intentionally walked before Quinlan, batting for Jeff DaVanon, singled sharply to left.
Kelvim Escobar (3-2) allowed one hit over three innings for the win.
Detroit starter Jason Johnson allowed four runs and 10 hits in six innings, leaving with a 6-4 lead.
Jimmy Rollins extended his hitting streak to 22 games with a two-run homer that Juan Encarnacion nearly caught, then added a two-run double to help Philadelphia beat Florida 13-3 on Friday.
The Phillies, starting a nine-game trip, won for the fifth time in six games. They remained one-half game behind NL wild-card leader Houston, and the Marlins fell 1 1/2 games back with their third consecutive loss.
Rollins' 10th homer made the score 2-all in the third. Encarnacion retreated to the right-field wall and jumped in a bid to make the catch, but the ball glanced off the webbing of his glove and into the seats.
Rollins' double broke open the game in the sixth, when four Florida relievers walked three and allowed five runs, all with two outs. Pinch-hitter Michael Tucker's two-run single put the Phillies ahead to stay.
Kenny Lofton had five singles for the Phillies, who had 17 hits.
Jon Lieber (15-12) beat Florida for the second time in six nights. He pitched five innings and allowed two runs, both on Carlos Delgado's 31st homer. Five relievers completed a seven-hitter.
Astros 2, Brewers 1
At Houston, Jeff Bagwell hit a run-scoring single in the ninth and Houston won its third straight.
With the score 1-1, Mike Lamb and Lance Berkman hit consecutive singles against Dana Eveland (1-1). After two outs, Bagwell pinch hit for Brad Lidge (4-3) and singled to right-center. It was Bagwell's third appearance since he returned Sept. 9 after recuperating from shoulder surgery in May.
Houston's Roy Oswalt allowed one run and eight hits in 7 1-3 innings. Rick Helling, trying to beat Houston for the second time in six days, gave up one run and four hits in seven innings.
Lyle Overbay homered for the Brewers.
Cubs 5, Cardinals 3
At Chicago, Jeromy Burnitz had two hits and three RBIs and Derrek Lee hit his 44th homer for Chicago.
St. Louis clinched its fourth National League Central division title in six years on Thursday, and even though it has the tiebreaker over second-place Houston if the teams finish with 94 wins, the Cardinals are holding off on a victory party until they get one more win.
Jim Edmonds hit his 28th homer for St. Louis.
Chicago's Glendon Rusch (7-8) allowed three runs on seven hits in 6 2-3 innings.
Ryan Dempster pitched the ninth for his 28th save.
Matt Morris (14-9) lost his fourth straight start and fell to 0-4 against the Cubs, allowing four runs on seven hits in six innings.
Giants 5, Dodgers 4
At San Francisco, Barry Bonds hit his first homer after a season-long layoff and Todd Linden singled in the winning run with one out in the bottom of the ninth for San Francisco.
Bonds, who missed most of the year recovering from three operations on his right knee since Jan. 31, hit his 704th career homer in the first off Brad Penny.
Pinch-hitter Ricky Ledee tied the game with a two-run single in the eighth for the Dodgers, but Linden, who had replaced Bonds in left field, got the game-winning hit off Duaner Sanchez (4-6).
Bonds is third on the career homer list, trailing only Babe Ruth (714) and Hank Aaron (755). His homer gave the Giants a 2- lead and came three batters after Randy Winn led off with his career-high 15th home run.
Bonds' first RBI of the season moved him into a ninth-place tie on the career list with Carl Yastrzemski with 1,844.
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