Mark Prior struck out a season-high 11 for the Cubs in his seven innings, but gave up solo home runs to Ken Griffey Jr. and Edwin Encarnacion. He allowed eight hits and three runs and didn't walk a batter. Will Ohman (2-2) took the loss.
Aaron (8-10) allowed eight hits, striking out three and walking none in seven innings.
Griffey led off the sixth with his 25th home run to tie the game at 2-all. Nomar Garciaparra's first home run of the season gave the Cubs the lead again.
But Encarnacion's leadoff homer, his second of the season, tied it in the seventh before the Reds' outburst in the last two innings.
Nationals 6, Astros 5
At Houston, Brandon Watson homered and doubled in his major league debut, and slumping Washington started a pivotal road trip by beating Houston.
Brad Wilkerson, Brian Schneider and Vinny Castilla also homered for the Nationals, who snapped a 13-game losing streak in one-run games.
Washington homered four times for the first time this season to win their first one-run decision since July 8.
Morgan Ensberg homered twice for the Astros, who lead the Nationals by one game in the NL wild-card race. Ezequiel Astacio (2-5) allowed five runs and six hits in four innings.
John Patterson (6-3) earned the win despite allowing five runs in 5 2-3 innings, and Chad Cordero got the final three outs in the ninth for his major league-leading 37th save.
Cardinals 5, Brewers 2
At Milwaukee, Anthony Reyes threw 6 1-3 innings of two-hit ball in his major league debut and Mark Grudzielanek had two RBIs to lead St. Louis over Milwaukee.
Reyes (1-0), a 23-year-old right-hander in only his second full season in professional baseball, was just the sixth starting pitcher for the Cardinals this season. He was expected to be shipped back to Triple-A Memphis on Wednesday.
He allowed two earned runs on two hits with one walk and five strikeouts.
Jason Isringhausen pitched the ninth for his 30th save in 33 chances.
Pirates 12, Rockies 4
At Denver, Jason Bay homered and drove in four runs, and Dave Williams pitched six strong innings as Pittsburgh thrashed Colorado.
The Pirates had nine runs -- all off Rockies starter Jose Acevedo (2-2) -- and 14 hits by the fourth inning, finishing with 19.
Jack Wilson had two RBIs, Jose Castillo had four hits and Bay had three for Pittsburgh.
Williams (9-8) allowed a run and six hits.
Padres 8, Mets 3
At San Diego, Brian Giles and Khalil Greene homered for the Padres, who handed Pedro Martinez his worst start of the year.
With Park Chan-ho (1-0) striking out a season-high eight in his home debut, the NL West-leading Padres won their fifth straight game and for the sixth time in seven games. Their hot streak follows a span in which they lost 12 of 13, including being swept in a three-game series at New York July 19-21 that started an 0-6 road trip.
Greene had three hits and scored three runs. New York's Jose Reyes went 0-for-4, ending what was the majors' longest active hitting streak at 20.
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