Duke (1-0) allowed five extra-base hits among the six he gave up, but repeatedly got big outs while stranding seven runners and beating Brett Myers (6-5). Jose Mesa earned his 21st save.
Padres 7, Astros 5
At Houston, Ramon Hernandez capped a six-run fifth inning with a two-run single in his first game back from the disabled list, and San Diego ended a three-game losing streak.
Hernandez, who had been out with a sprained left wrist, played for the first time since June 18.
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