Virginia's defense also played a huge role, not allowing quarterback Joel Statham to follow up his 333-yard performance in a 20-17 victory against Florida State last week.
No. 13 Florida St. 29, Duke 7
In Tallahassee, Florida, backup quarterback Wyatt Sexton led three long scoring drives in the second half, and Gary Cismesia tied a school record with five field goals in his college debut.
Sexton completed 11 of 15 passes for 220 yards and a touchdown while taking the Seminoles (7-2, 5-2 ACC) on drives of 93, 80 and 70 yards to break open a tight game with 20 straight points. Sexton replaced Chris Rix, who failed to get the Seminoles into the end zone in the first half.
The Blue Devils fell to 1-8 and 0-6 in conference play.
No. 15 West Virginia 42, Temple 21
In Morgantown, West Virginia, Kay-Jay Harris caught two scoring passes and ran for two other touchdowns to lead West Virginia.
West Virginia's Chris Henry, benched for the first half after being ejected last week against Rutgers, caught a 40-yard TD pass from Rasheed Marshall late in the third quarter. Henry, who had two unsportsmanlike penalties last week, flipped the ball around his body after the scoring catch. The ball hit a Temple player, but Henry, motioning that it was meant for the referee, wasn't flagged.
No. 18 Virginia Tech 27,
North Carolina 24
In Chapel Hill, North Carolina, Mike Imoh ran for 236 yards and two touchdowns and the Hokies survived a late North Carolina rally, which fell short when the Tar Heels missed a tying 54-yard field goal with about a minute left.
The Tar Heels, who upset Miami last week on a last-play field goal by freshman Connor Barth, seemed poised for more late-game heroics. North Carolina drove to the Tech 26 in the closing minutes, but an 11-yard sack of Darian Durant on third down made Barth's job much tougher. His 54-yard attempt fell short.
No. 20 Iowa 23, Purdue 21
In Iowa City, Iowa, Drew Tate threw two touchdown passes and Iowa 7-2, 5-1 Big Ten forced five turnovers and blocked two field goals to run its home winning streak to 17, the fourth-longest string in the nation.
Brandon Kirsch, starting in place of the injured Kyle Orton, threw three touchdown passes for Purdue. But his miscues in the fourth quarter, one fumble and two interceptions, scuttled Purdue's attempt to rally from a 17-point deficit.
Kirsch was 25-of-42 for 280 yards, including a 10-yard TD pass to Taylor Stubblefield in the final minutes. Stubblefield finished with 15 catches for 153 yards.
Cincinnati 52, S Mississippi 24
In Hattiesburg, Mississippi, Gino Guidugli threw three of his Cincinnati-record five touchdown passes to Hannibal Thomas.
Guidugli was 19-of-26 for 308 yards for Cincinnati (5-4, 4-2 Conference USA), which snapped the Golden Eagles' 13-game league winning streak and beat a ranked team for the first time in four years.
No. 23 Arizona St. 34, Stanford 31
In Tempe, Arizona, Andrew Walter threw 4 yards to Matt Miller -- his fourth touchdown pass of the night -- with 9 seconds to play to give Arizona State (7-2, 4-2 Pac-10) a wild victory over Stanford (2-4, 4-5).
Backup quarterback T.C. Ostrander gave the Cardinal a 31-26 lead with a 67-yard TD pass to Alex Smith with 2:02 remaining.
But Walter, who was 28-for-43 for 415 yards and broke John Elway's Pac-10 record for career touchdown passes, was 4-for-8 for 79 yards on a 13-play, 80-yard drive for the winning score. Walter has 80 TD passes, breaking Elway's record at Stanford of 77.
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