The Cardinals have swept 11 series, nine of three or more games, and are 10-2 against the Mets the last two years.
Leiter (8-4) lasted only four innings. He gave up six runs on eight hits, and walked four and hit two batters. He saw his ERA soar 40 points to 2.52, which is still tops in the majors.
Reds 14, Rockies 7
In Denver, Wily Mo Pena homered and had a career-high five RBIs before leaving in the sixth inning with cramps and dehydration in the Reds' victory.
Pena, who has 11 home runs and 27 RBIs in his last 26 games, was 3-for-4 with two singles and his career-best 18th homer to help the Reds salvage the finale of the three-game series.
Felipe Lopez, D'Angelo Jimenez, Jason LaRue and Sean Casey drove in two runs each for the Reds, who set season highs with 14 runs and 16 hits.
Cory Lidle (7-10) benefited from the offensive surge, allowing three runs and nine hits over six innings in winning for the first time since June 30 at the New York Mets.
Jeff Fassero (2-8) allowed a career-high 11 runs and 11 hits in three-plus innings.
Phillies 4, Dodgers 1
In Los Angeles, Brett Myers pitched two-hit ball for eight shutout innings and struck out a season-high nine, leading the Philadelphia Phillies over the Dodgers.
Dodgers starter Brad Penny jumped off the mound in pain in the first inning and left with a strained right biceps. It was just his second outing for Los Angeles since he was acquired in a trade with Florida. Penny (9-9) is scheduled for an MRI on Monday.
Myers (7-8) held the Dodgers hitless until the sixth, allowed only four baserunners and combined with Tim Worrell on a four-hitter. Worrell gave up an RBI double to Shawn Green with two outs in the ninth.
Chase Utley hit a solo homer two batters before Penny left. Bobby Abreu drove in his 80th run with a sacrifice fly, helping the Phillies conclude their longest road trip of the season with a 6-7 record after losing six of the first seven games. They took two of three against the Dodgers and won the season series 5-1.
Giants 6, Cubs 3
In San Francisco, rookie Noah Lowry had another impressive start and Dustan Mohr made a run-saving diving catch in the warning track dirt in the eighth inning of San Francisco's win over Chicago.
Lowry (2-0) also added a second-inning single and a double in the fourth, giving him four straight hits over his past two starts until a groundout in the sixth.
The Giants moved within two games of the Cubs in the National League wild card race, tied with San Diego.
Toronto Blue Jays manager Carlos Tosca was fired Sunday and replaced by first-base coach John Gibbons.
Struggling through a disappointing season, the Blue Jays fired Tosca, a native of Cuba, less than an hour after they were beaten by the New York Yankees for their fifth straight loss.
Gibbons will be the interim manager for the rest of the season.
"We have six or seven weeks left in the season and the team showed signs of not playing hard," said general manager J.P. Ricciardi, who hired Tosca on June 3, 2002. "We have an obligation to try and do as well as we can. It wasn't an easy decision. It never is when you have to tell someone who does what he loves that it's being taken away from him."
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