Farina Elia rallied to beat Belgium's Els Callens 3-6, 6-2, 6-1. Koukalova upset Russian Dinara Safina 6-4, 7-6 (2) and Sprem beat Cara Black of Zimbabwe, 6-4, 6-3.
In late first-round action, Julia Vakulenko of Ukraine beat US player Alexandra Stevenson 6-3, 6-1 and Iveta Benesova, another Czech qualifier, defeated Greece's Eleni Daniilidou 7-5, 6-4.
In front of some 3,000 home fans at the Sports Palace, Clijsters immediately took charge of the match, winning the opening three games and riding her dominant serve to an easy first-set win in half an hour.
The second set offered more of the same -- a confident Clijsters against an error-prone Parra -- and the Belgian wrapped up the match in just over an hour.
"There is a great atmosphere here. It makes it all the more enjoyable," said Clijsters of the adoring crowd.
She is seeking her second tournament victory in a row after winning the Gaz de France tournament in Paris last weekend.
Henin-Hardenne will meet Chladkova today, and the world's top two players are expected to meet in another all-Belgian final on Sunday, each seeking her first win in Antwerp.
Henin-Hardenne beat Clijsters for the Australian Open title three weeks ago.
Double defending champion Venus Williams pulled out of the tournament after aggravating a knee injury. A third victory for Williams would have given her the right to keep the tournament's first prize, a US$1.3 million diamond-studded racket.
ABN Amro
Lleyton Hewitt of Australia cruised into the second round of the ABN Amro tournament Wednesday, defeating Fernando Gonzalez of Chile 6-2, 6-1.
"I took a week to rest after the Davis Cup, and I feel fresh," said the sixth-seeded Hewitt, adding he kept Gonzalez "under strong pressure" throughout the match by aiming most of hits shots at the Chilean's weaker backhand.
Top-seeded Roger Federer of Switzerland extended his winning streak to 15 matches by beating Arnaud Clement of France 6-4, 6-3.
Second-seeded Juan Carlos Ferrero of Spain, who beat qualifier Dennis Van Scheppingen 6-3 7-6 (5), stormed to a 5-0 first-set lead in just 12 minutes.
Earlier in the day, defending champion Max Mirnyi of Belarus beat Sargis Sargsian of Armenia 6-7 (3), 7-6 (5), 6-1, surviving a match point in the second set.
"I didn't change tactics after losing the first set," the big-serving Mirnyi said. "I just kept playing my own game and especially focusing on my first service."
Rainer Schuettler of Germany was the first quarterfinalist, defeating Radek Stepanek of the Czech Republic 6-3, 6-4.
Hewitt's second-round opponent will be 2002 Australian Open champion Thomas Johansson of Sweden, who steamrollered Thierry Ascione of France 6-3, 6-1.
Czech qualifier Tomas Cakl needed two tiebreakers and five match points to make a winning debut on the ATP tour, upsetting Jonas Bjorkman of Sweden 7-6 (2), 7-6 (8).
Kroger St. Jude
Sixth-seeded James Blake of the US got past Wesley Moodie of South Africa 7-6 (5), 6-1 Wednesday in the second round of the US$880,000 Kroger St. Jude.
Blake now faces Joachim Johansson of Sweden, who beat him last week in San Jose.
In the women's tournament, defending champion Lisa Raymond of the US defeated qualifier Galina Voskoboeva of Russia 6-2, 6-3; Gisela Dulko of Argentina beat fifth-seeded American Ashley Harkleroad 7-5, 7-6 (3); and third-seeded Maria Sharapova of Russia advanced when countrywoman Tatiana Panova quit because she was having trouble breathing.
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