Daunte Culpepper threw for 277 yards in his return to the lineup, Minnesota's defense knocked Steve Beuerlein out of the game, and the Vikings beat the Denver Broncos 28-20 on Sunday.
Randy Moss had 10 catches for 151 yards, and his lateral to Moe Williams on the final play of the first half led to a 59-yard touchdown play for Minnesota (6-0).
The Vikings' first five victories came against opponents with a combined record of 8-20.
The Broncos (5-2) nearly rallied behind third-string quarterback Danny Kanell, who went 12-for-18 for 104 yards and a touchdown after Beuerlein hurt a finger on his passing hand.
Titans 37, Panthers 17
In Charlotte, North Carolina, Carolina picked up its first loss by losing four fumbles that led to scores.
Steve McNair threw for one touchdown and ran for another, and Keith Bullock scored on a 35-yard fumble recovery for Tennessee (5-2). The Titans also scored with a 50-yard pass play on a fake punt.
Stephen Davis gained just 20 yards on 11 carries for the Panthers (5-1).
Eagles 14, Giants 10
In East Rutherford, New Jersey, Brian Westbrook scored on an 84-yard punt return with 1:16 to play for the Eagles (3-3).
Until the return, the Giants' defense dominated the game between the two struggling NFC East teams. It had limited Donovan McNabb and the Eagles to 134 yards and one second-half first down.
The Giants (2-4) limited McNabb to 9-for-23 passing for 64 yards.
Chargers 26, Browns 20
In Cleveland, LaDainian Tomlinson ran for 200 yards and a touchdown, helping San Diego end a nine-game losing streak that dated to last season.
Steve Christie kicked field goals of 44, 50, 43 and 32 yards, and Kwamie Lassiter returned an interception 38 yards for a TD for the Chargers (1-5), who entered as the NFL's lone winless team.
Kelly Holcomb replaced an ineffective Tim Couch late in the third quarter and threw two TD passes as the Browns (3-4) trimmed a 17-point deficit to 23-20.
Patriots 19, Dolphins 13, OT
In Miami, Tom Brady hit Troy Brown on an 82-yard scoring play in overtime for the Patriots (5-2), who moved atop the AFC East.
New England ended and 0-for-13 skid at Miami (4-2) in September and October.
The Dolphins had two chances to win the game. But Olindo Mare had a field-goal attempt blocked near the end of regulation and missed another one in overtime.
Bengals 34, Ravens 26
In Cincinnati, Baltimore rookie QB Kyle Boller fumbled twice and threw an interception, setting up a 24-point swing that allowed Cincinnati head coach Marvin Lewis beat the team he helped win a Super Bowl as defensive coordinator.
After a couple of slop-time touchdowns got the Ravens close, the Bengals (2-4) recovered the onside kick and ran out the clock.
At 3-3, the Ravens remained in first place in the AFC North.
Cowboys 38, Lions 7
In Detroit, Terry Glenn caught three first-half touchdown passes to help Dallas (5-1) matched its win total from each of the past three seasons.
Under new coach Bill Parcells, the Cowboys have won five straight games for the first time since 1994.
Rams 34, Packers 24
In St. Louis, Marc Bulger threw three touchdown passes, and Isaac Bruce became the 18th player in NFL history to top 10,000 yards receiving as St. Louis improved to 4-2.
Brett Favre threw two touchdown passes for Green Bay (3-4), but his effort at a comeback fizzled after a 1-yard TD toss to William Henderson pulled Green Bay within 21-17 in the third quarter.
Ahman Green entered with three straight 100-yard rushing games, but St. Louis held him to 35 yards on 20 carries.
Saints 45, Falcons 17
In Atlanta, Aaron Brooks threw for 352 yards and three touchdowns, and Deuce McAllister scored twice to lead New Orleans (3-4).
Atlanta _ blown out 36-0 by St. Louis last Monday night -- fell behind 35-14 at the half by giving up a staggering 369 yards.
49ers 24, Buccaneers 7
In San Francisco, Terrell Owens made a 75-yard scoring romp through Tampa Bay's defense, and Garrison Hearst ran for 117 yards and a touchdown to lead San Francisco (3-4).
Owens had six catches for 152 yards, but he also dropped two potential TD passes in the second half.
Seahawks 24, Bears 17
In Seattle, Shaun Alexander's 25-yard touchdown run with 58 seconds left lifted Seattle to the best start in franchise history, 5-1. Alexander gained 101 yards on 21 carries, scoring twice.
Seattle's Marcus Trufant sealed the win when he intercepted a pass by Chris Chandler with 37 seconds on the clock. Chicago (1-5) lost for the 17th time in its last 20 games.
Bills 24, Redskins 7
In Orchard Park, New York, Travis Henry ran for a career-high 167 yards and scored twice, and Josh Reed had eight catches for 109 yards and a touchdown for Buffalo (4-3).
The Redskins (3-4) lost their third straight game and played the final nine minutes without starting quarterback Patrick Ramsey. He bruised his right (throwing) hand when he was sacked by Aaron Schobel.
Jets 19, Texans 14
In Houston, Vinny Testaverde led New York (2-4) on a long drive in the waning minutes to set up an 8-yard TD run by LaMont Jordan with 1:21 left.
J.J. Moses returned the ensuing kickoff 63 yards to the Jets 27, and Houston (2-4) quickly moved to the 9. But on fourth-and-4, David Carr's pass glanced off receiver Andre Johnson's chest and fell to the ground.
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