Helton hit a two-run homer in the first inning off Odalis Perez (4-3), a solo shot in the fourth against Perez and another two-run homer in the eighth off Eric Gagne. Helton, who has 10 homers this season, also singled in a run in the third.
Helton, who also homered three times at Coors Field on May 1, 2000, had his 22nd multihomer game, his first this season.
Mets 5, Phillies 0
In Philadelphia, Steve Trachsel pitched 6 2-3 shutout innings as New York blanked a hapless Philadelphia.
Cliff Floyd had a two-run double and Rey Sanchez, Jeromy Burnitz and Tony Clark each had RBI doubles for the Mets, who have won four of six against Philadelphia in two weeks.
Trachsel (4-2) allowed five hits, struck out five and walked three to win his fourth consecutive start.
Expos 3, Marlins 2
In Miami, Orlando Cabrera's bloop RBI single capped a three-run rally in the seventh inning that carried Montreal over Florida.
Montreal avoided being swept in a four-game series for the first time since 2000.
Florida had won six straight for the first time since Sept. 26 to Oct. 1, 2000.
Montreal's Japanese pitcher Tomo Ohka (4-5) allowed two runs and seven hits in six innings.
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