In Cleveland, Brian Anderson scattered seven hits over six innings to lead the Indians 5-2 past the Chicago White Sox.
Anderson (2-0) gave up two runs while striking out two and walking two. Danys Baez got the last five outs to earn his third save.
Chicago's Jon Garland (0-1) allowed five runs on six hits over six innings. He struck out two and walked four.
Brandon Phillips had a solo homer and two hits for the Indians, while Karim Garcia drove in a pair of runs.
Royals 9, Tigers 6
Dee Brown hit his first career grand slam home run as the Kansas City Royals continued their unbeaten start to the season, beating the winless Detroit Tigers 9-6 on Wednesday.
Brent Mayne added a three-run homer for the Royals, who are off to a franchise-best 6-0 start.
Yankees 2 Twins 1
In New York, Jorge Posada and Raul Mondesi both homered to lead the Yankees to a 2-1 win over the Minnesota Twins.
Mike Mussina (2-0) beat the Twins for the 19th time in 21 decisions by allowing an unearned run on six hits over eight innings before Juan Acevedo pitched a scoreless ninth for his second save.
Blue Jays 10 Red Sox 5
In Toronto, Vernon Wells hit a grand slam home run to lead the Blue Jays to their fifth straight victory, a 10-5 decision over the Boston Red Sox.
Tanyon Sturtze (2-0) won his second straight win after losing 18 games last season for Tampa Bay. He allowed three runs on six hits over seven innings, striking out five and walking one.
Devil Rays 10 Orioles 7
In St. Petersburg, Rocco Baldelli hit a tie-breaking RBI triple in the seventh inning as the Tampa Bay Devil Rays beat the mid-table Baltimore Orioles 10-7.
Marlon Anderson hit a three-run homer and drove in four runs for Tampa Bay, while Aubrey Huff had two hits and drove in three runs.
Al Levine, called up from the minors before the game, pitched a hitless 2 2/3 innings of relief for the win while Lance Carter pitched a scoreless ninth for his first save.
Athletics 13 Rangers 5
In Arlington, Terrence Long, Mark Ellis, Miguel Tejada and Scott Hatteberg all homered for the Oakland Athletics in their 13-5 victory over the Texas Rangers.
Mark Mulder allowed four runs on nine hits while striking out four and walking two.
Texas's Ismael Valdes (1-1) went four innings, allowing eight runs on seven hits on six strikeouts and two walks.
Angels 5 Mariners 1
In Seattle, Kevin Appier allowed just six hits over six innings as the Anaheim Angels beat the Seattle Mariners 5-1.
Appier (1-1) gave up one run while striking out four and walking two. Scott Spiezio homered, had three hits and drove in three runs.
RSS