Bryant's basket from the top of the key came off Robert Horry's inbounds pass with 3.3 seconds remaining. It gave Bryant 21 points, including 10 in the fourth quarter.
Shaquille O'Neal led the Lakers with 33 points and 19 rebounds, hitting 13 of his 20 shots from the floor. Los Angeles won for the sixth time in seven games.
Memphis, which has lost six straight, was led by 18 points each from Jason Williams and Pau Gasol.
Bucks 95, Cavaliers 93
In Milwaukee, Michael Redd scored 22 points and combined with Toni Kukoc to dominate the second half as the Milwaukee Bucks moved closer to a playoff berth.
The Bucks reduced their magic number to three over Washington in the race for the East's final playoff berth. Any combination of three Milwaukee victories and/or Washington losses gives the berth to the Bucks.
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