Problems sleeping may be an early sign of Alzheimer’s if a study in mice also applies to people, say researchers.
Clumps of protein, called plaques, in the brain are thought to be a key component of the illness. A study, published in the journal Science Translational Medicine, showed that when plaques first developed, the mice started having disrupted sleep.
The hunt for early hints that someone is developing Alzheimer’s is thought to be crucial for treating the disease. People do not show problems with their memory or clarity of thought until very late on in the disease. At this point, parts of the brain will have been destroyed, meaning treatment will be very difficult or maybe even impossible.
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照片:法新社
Levels of the beta amyloid protein naturally rise and fall over 24 hours in both mice and people. However, the protein forms permanent plaques in Alzheimer’s disease. Experiments at Washington University showed that nocturnal mice slept for 40 minutes during every hour of daylight. However, as soon as brain plaques started to form the mice were sleeping for only 30 minutes.
(Liberty Times)
研究人員說,如果一份老鼠研究適用人類,睡不好可能是阿茲海默氏症的初期跡象。
腦中的蛋白質塊,也就是所謂的斑塊,被視為這種病症的關鍵成分。刊登在《科學轉譯醫學期刊》的研究顯示,當斑塊初期發展時,老鼠開始出現睡眠中斷。
追蹤阿茲海默氏症患者的初期徵兆,被視為治療這種疾病的關鍵。阿茲海默氏症患者直到非常晚期,才會出現記憶力或思慮清晰問題,到此時大腦部分區塊已經受創,治療會非常困難或甚至不可能。
人類和老鼠腦內的乙型澱粉樣蛋白含量二十四小時之間會自然上升或下降,但這種蛋白會在阿茲海默氏症患者腦內形成永久斑塊。華盛頓大學實驗發現,夜行性老鼠白天每小時睡四十分鐘,但當腦內斑塊開始形成,老鼠只睡三十分鐘。
(自由時報/翻譯:自由時報國際新聞中心)
Tangbao are one of the most internationally renowned delicacies, that win the hearts of both locals and tourists. Their charm lies in the paper-thin flour wrapper that needs to be folded evenly almost 20 times. Folding a tangbao requires skill to deal with a bulging filling and a thin wrapper. Tangbao are served in a bamboo steamer in which they are steamed, not only adding to the visual appearance, but ensuring they do not get cold before reaching the table. The best way to enjoy a tangbao is to dip it in a mixture of vinegar and soy sauce with
The Bank of Japan (BoJ) announced a seismic change in direction on March 19, hiking interest rates for the first time in 17 years. The move represents an unwinding of an ultra-loose — and maverick -- policy aimed at putting Japan’s “lost decades” of stagnation and deflation behind it. The last time the BoJ raised interest rates was in 2007, but its war against deflation began in earnest in 2013 under then-prime minister Shinzo Abe. “Abenomics” combined generous government spending and central bank monetary easing. The BoJ spent vast amounts on bonds and other assets to pump liquidity into the
A: Wow, YouTuber Xander 73’s channel “73_Tricking” now has over 10 million subscribers, making him Taiwan’s first 10-million YTR. B: Cool! But what’s “tricking?” A: Basically, it’s a sport derived from extreme martial arts. B: Xander 73’s income is as high as NT$600,000 per month. What’s the secret of his success? A: He often uses English catchphrases in his videos to attract more viewers from around the world. This shows how important English is. A: 哇,YouTuber奇軒的「奇軒Tricking」頻道訂閱突破千萬人, 成為台灣首位千萬YTR! B: 好厲害,但什麼是tricking啊? A: 聽說是極限武術所衍生的運動。 B: 奇軒月入60萬,成功的秘訣是什麼呢? A: 他常使用英文標語,所以能吸引全球觀眾,可見英文多重要。 (By Eddy Chang, Taipei Times/台北時報張聖恩)
Have you ever wished for an extra hour to prepare for exams or finish homework? In some countries, people actually adjust their clocks to gain or lose an hour, all for the sake of Daylight Saving Time (DST). Specifically, clocks are set forward by an hour in March and then set back in November. One of the primary reasons for implementing DST is to make better use of natural daylight so that people can reduce energy consumption. The concept originated with Benjamin Franklin in 1784 and became widely adopted during World War I. Today, this system is in place