A survey for the Licensed Vintners Association (LVA), representing 750 pubs in Dublin, said compliance was excellent in the capital but sales are down by 16 percent.
It claims 2,000 full and part-time jobs are being lost in the Dublin pub trade alone.
LVA chief executive Donall O'Keeffe said it confirmed the "harsh reality of the economic impact of the ban."
"The majority of Dublin publicans have described the current business climate as being very unfavorable -- without a doubt, the smoking ban has compounded this state of affairs," he said.
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