India has granted Pfizer Inc a patent for its powerful pneumonia vaccine Prevenar 13, in a blow to some health groups that said this would put the treatment out of reach of thousands in poorer nations.
The decision by India’s patent office bars other companies from making cheaper copies of the vaccine and allows Pfizer to exclusively sell it in India until 2026.
It is a big victory for the US drugmaker in a market that has the world’s largest number of pneumonia cases, a lung disease that kills nearly a million children a year globally.
The decision also has international implications, as several poorer nations rely on India’s robust drugs industry to supply cheaper copies of medicines and vaccines.
It also comes at a time of ongoing US pressure on India to tighten its patent laws. The Office of the US Trade Representative expressed concerns about India’s intellectual property (IP) laws in a report in June, and listed it among countries whose IP laws unfairly favor local companies.
Pfizer’s vaccine protects children and adults from 13 types of pneumococcal bacteria, and a full vaccination course costs about US$170 on India’s private market.
India started giving out the vaccine for free under its national immunization program earlier this year, but the rollout like that of most vaccines in the program, is in phases, so only about 2.1 million of the 25 million eligible people in the country will get it this year.
The patent grant means Indian companies will not be able to make the vaccine for domestic use, or exports.
“Manufacturers will have to find new routes to develop a non-infringing [pneumonia] vaccine, which may delay the availability of competing products in the pipeline from Indian producers,” the medical charity Medecins Sans Frontieres (MSF) said in a statement.
MSF filed an objection to Pfizer’s patent request last year on the grounds that a patent would deprive many developing nations of cheaper copies.
At least one Indian company, Panacea Biotec Ltd, is developing a cheaper form of the vaccine, and had also filed an opposition to Pfizer’s patent request last year.
A source familiar with the matter said Panacea is considering filing a post-grant opposition.
MSF said it was reviewing its legal options in the matter.
Pfizer’s patent on the same vaccine was revoked by the European Patent Office last year, and is being challenged in South Korea and the US, MSF said.
The pharmaceutical giant has made the vaccine available at discounted prices under the Global Alliance for Vaccines and Immunization (GAVI) — an international public-private partnership to improve access to vaccines in the world’s poorest countries. More than 50 countries are eligible to procure the vaccine through GAVI, according to the organization’s Web site.
Following criticism over the high price of Prevenar 13, Pfizer reduced the vaccine price to non-governmental organizations in November last year, seeking to protect vulnerable people from illness in humanitarian crises.
Pfizer welcomed the granting of the patent, saying each dose of Prevenar 13 takes two-and-a-half years to produce, and the vaccine was launched in India in 2010.
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