The Shanghai A-share Index fell 4.83 points to 1,331.64 and the Shenzhen A-share Index was down 1.04 points or 0.32 percent at 319.26.
The benchmark Shanghai Composite Index, which covers A and B-shares, fell 4.73 points or 0.37 percent at 1,269.46.
Sydney share prices closed off record highs as late profit taking sent the market into negative territory and offset positive sentiment from gains in New York overnight.
Dealers said traders who had been riding the strong market over the past couple of days had begun taking profits, seeing only limited potential upside left and unwilling to take the risk of holding positions over the weekend.
The S&P/ASX 200 lost 6.2 points or 0.12 percent to 4,971.7, off an intra-day record high of 4,997.8 points.
Singapore
Singapore share prices closed 0.18 percent lower, pulled down by losses in key technology stocks.
The Straits Times Index fell 4.52 points to 2,494.41.
Kuala Lumpur share prices closed flat in cautious trade ahead of the weekend amid concerns over two new outbreaks of bird flu in the country.
The composite index slipped 0.53 points at 922.62.
Bangkok share prices closed 0.20 percent higher, led by gains in energy stocks, but the broader market was kept in check due to ongoing political uncertainty.
Dealers said foreign investors continued to stay on the sidelines as they were wary of the prolonged leadership crisis.
The composite index edged up 1.47 points to 741.43.
Manila share prices closed up 0.39 percent, hitting their highest level in six weeks as investors bought bank stocks amid an improved outlook for the sector.
The composite index added 8.40 points to 2,150.17.
Mumbai share prices fell 0.17 percent as funds and retail investors booked profits at higher levels, with selling pressure seen in power, automobile and banking stocks.
The benchmark 30-share SENSEX index closed 18.7 points lower at 10,860.04.
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